Hormone Rebalance - Studies

Black Cohosh

The study showed that black cohosh extracts significantly improved overall menopausal symptoms, particularly hot flashes and somatic complaints, compared to placebo.

Sadahiro, R., Matsuoka, L. N., Zeng, B.-S., Chen, K.-H., Zeng, B.-Y., Wang, H.-Y., Chu, C.-S., Stubbs, B., Su, K.-P., Tu, Y.-K., Wu, Y.-C., Lin, P.-Y., Chen, T.-Y., Chen, Y.-W., Suen, M.-W., Hopwood, M., Yang, W.-C., Sun, C.-K., Cheng, Y.-S., … Tseng, P.-T. (2023). Black cohosh extracts in women with menopausal symptoms: An updated pairwise meta-analysis. Menopause, 30(7), 766–773.

Sage

The randomized controlled trial found that daily intake of 100 mg sage (Salvia officinalis) extract for four weeks significantly reduced the severity of hot flashes, night sweats, panic, fatigue, and improved concentration in postmenopausal women

Dadfar, F., & Bamdad, K. (2019). The effect of Salvia officinalis extract on the menopausal symptoms in postmenopausal women: A randomized controlled trial.

International Journal of Reproductive Biomedicine, 17(4), 287–292.

Soy Isoflavones

The study found that supplementation with soy isoflavones daily for 12 weeks significantly reduced menopausal symptoms—especially somatic and psychological—and was more effective in perimenopausal women (38.6% improvement) than in postmenopausal women (33.3% improvement)

Khapre, S., Deshmukh, U., & Jain, S. (2022). The impact of soy isoflavone supplementation on the menopausal symptoms in perimenopausal and postmenopausal women.

Journal of Mid-life Health, 13(2), 175–184.

Red Clover

The study showed that red clover extract significantly reduced the frequency of menopausal hot flashes compared to placebo

Gartoulla, P., & Han, M. M. (2014). Red clover extract for alleviating hot flushes in postmenopausal women: A meta-analysis. Maturitas, 79(1), 58–64.

Kanadys, W., Barańska, A., Błaszczuk, A., Polz-Dacewicz, M., Drop, B., Kanecki, K., & Malm, M. (2021). Evaluation of clinical meaningfulness of red clover (Trifolium pratense L.) extract to relieve hot flushes and menopausal symptoms in peri- and post-menopausal women: A systematic review and meta-analysis of randomized controlled trials.

Nutrients, 13(4), 1258.